Clogged Pipes! Understanding the Pathology of Atherosclerosis

What’s atherosclerosis?

“Atheros” is Greek for a gruel or paste, and “sclerosis” means hardening. That is just what happens in the arteries of men and women with this disease. A paste-like material hardens overtime to create a plaque. The details are in how and just why are a lot more complicated.

The gruel-like materials comprises a number of different things. The first, as well as perhaps most important component, is low denseness lipoprotein (i.e.: LDL). LDL, or “bad cholesterol”, is an assortment of lipid (ie: excess fat and cholesterol) and health proteins. These molecules speed up the atherosclerotic process for reasons mentioned below.

So how exactly does LDL business lead to a plaque? The first rung on the ladder is disruption of your part of the bloodstream vessel known as the intimal covering.

Most arteries have 3 tiers: the intima, advertising, and adventitia. The intimal part is the part of the blood vessels vessel directly in touch with blood circulation.

The medial part is even muscle that control buttons the size of the blood vessels vessel; the adventitial level is a connective cells coating. Click to know more about the Tasigna atherosclerosis.


The symptoms of atherosclerosis are based mostly how large the plaques are, and where they can be found. A couple of three common symptoms of atherosclerosis:

(1) Angina (upper body pain)

(2) Transient ischemic disorders

(3) Vascular claudication

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